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Fig. 1 | Cell & Bioscience

Fig. 1

From: Impacts of plasma microbial lipopolysaccharide translocation on B cell perturbations and anti-CD4 autoantibody production in people with HIV on suppressive antiretroviral therapy

Fig. 1

Anti-CD4 IgG1 is the predominant subclass in PWH on ART. Plasma levels of anti-CD4 IgM (A), IgG1 (B), IgG2 (C), IgG3 (D), and IgG4 (E) were assessed by ELISA from healthy controls (n = 16), and PWH on ART with high (HIV+/antiCD4high, n = 8) versus low (HIV+/antiCD4low, n = 17) antiCD4IgG levels. ANOVA tests were used to analyze data. (F) Correlations between antiCD4IgG and subclasses. Spearman correlation tests. *, P < 0.05; **, P < 0.01; ****, P < 0.0001

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