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Fig. 3 | Cell & Bioscience

Fig. 3

From: Overexpression of HSF2 binding protein suppresses endoplasmic reticulum stress via regulating subcellular localization of CDC73 in hepatocytes

Fig. 3

HSF2BP overexpression inhibits inflammatory response induced by hepatic I/R. Liver is induced by 1-hour ischemia followed by 24-hour reperfusion in HSF2BP-TG and NTG mice. Sham mice received all procedures except for hepatic ischemia. Liver CD3, Ly6G and CD11b staining (A) and their quantitative results (B–D) after hepatic I/R in HSF2BP-TG and NTG mice. Original magnification, x400. The mRNA levels of liver TNF-α (E), IL-1β (F), IL-6(G), NLRP3 (H), MCP-1 (I), CXCL-1 (J), CXCL-10 (K) after hepatic I/R in HSF2BP-TG and NTG mice. Results are expressed as mean ± SE (n = 4–6/group) and compared by one-way ANOVA. * p < 0.05 versus sham mice, # p < 0.05 versus NTG mice

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Cell & Bioscience

ISSN: 2045-3701

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