Skip to main content
Fig. 2 | Cell & Bioscience

Fig. 2

From: Overexpression of HSF2 binding protein suppresses endoplasmic reticulum stress via regulating subcellular localization of CDC73 in hepatocytes

Fig. 2

HSF2BP overexpression protects against hepatic I/R injury. Liver is induced by 1-hour ischemia followed by 24-hour reperfusion in HSF2BP-TG and NTG mice. Sham mice received all procedures except for hepatic ischemia. A, Liver H&E staining after hepatic I/R in HSF2BP-TG and NTG mice. Original magnification, x100 and x200. Liver necrosis area (B) and histological score (C) after hepatic I/R in HSF2BP-TG and NTG mice. Serum AST (D) and ALT (E) after hepatic I/R in HSF2BP-TG and NTG mice. Liver TUNEL staining (F) and its quantitative result (G) after hepatic I/R in HSF2BP-TG and NTG mice. Original magnification, x200 and x400. Western blot analysis of cleaved-caspase 3 (H) and its quantitative result (I) after hepatic I/R in HSF2BP-TG and NTG mice. Results are expressed as mean ± SE (n = 4–6/group) and compared by one-way ANOVA. * p < 0.05 versus sham mice, # p < 0.05 versus NTG mice

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us