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Fig. 3 | Cell & Bioscience

Fig. 3

From: TMED3 promotes the development of malignant melanoma by targeting CDCA8 and regulating PI3K/Akt pathway

Fig. 3

TMED3 knockdown inhibited tumor growth of malignant melanoma in vivo. A A nude mice model of TMED3 knockdown was constructed via subcutaneous injection of A375 cells. B–D The fluorescence (B), volume (C) and weight (D) of xenograft tumors in shCtrl and shTMED3 groups were measured in indicated time. E The photos of tumors removed from mice models were collected. F The pattern of Ki-67 was detected by IHC analysis in tumor sections from shCtrl and shTMED3 mice models. The data were expressed as mean ± SD. ** P < 0.01, *** P < 0.001

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