Skip to main content
Fig. 5 | Cell & Bioscience

Fig. 5

From: A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet

Fig. 5

Evaluation of inflammatory responses. Representative images for the detection of astrocytes ac, and microglia df, co-stained with Hoechst for the detection of cellular nucleus (blue). Scale bar: 200 µm. Graphic representation of fluorescence intensity quantification for GFAP g and IBA1 h. In both cases, statistical analysis was performed through one-way ANOVA (n = 5) and Tukey’s post hoc test, * p < 0.05. ** p < 0.01 and *** p < 0.001. i. protein levels for TLR4 and PTP1B where two representative samples out of four or five per group are shown (n = 4–5). All results were represented as mean ± SD. Groups were compared against each other using one-way ANOVA and Tukey post-test, * p < 0.05 and ** p < 0.01

Back to article page