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Fig. 5 | Cell & Bioscience

Fig. 5

From: PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression

Fig. 5

PABPN1 suppresses Wnt signaling, cell cycle progression, and lipid biosynthesis of BC cells. A Western blot analysis of β-catenin expression in nucleus and cytoplasm of BC cells. α-Tubulin and Histone H3 were used as loading controls for cytoplasmic and nuclear fractions, respectively. B Cell cycle distribution of indicated BC cells analyzed by flow cytometry. C The neutral lipids content in indicated cells detected with BODIPY 493/503 dye (green). Nuclei were stained with Hoechst (blue). 200 × . Data are presented as the mean ± SD of three independent experiments. * P < 0.05

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