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Fig. 2 | Cell & Bioscience

Fig. 2

From: PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression

Fig. 2

PABPN1 inhibits the progression of BC cells. A The qRT-PCR and western blot analysis of PABPN1 levels in BC cells stably overexpressed, or silenced for PABPN1. B Proliferation abilities of BC cells determined using the CCK-8 assay. C Representative pictures of migrating and invading cells analyzed by Transwell assay. 200 × . D Xenograft tumors of nude mice from indicated groups. E Tumor volumes measured every third day. F Tumor weight of all mice in each group. G Pulmonary metastasis of BC cells detected using In Vivo Optical Imaging System. H Survival curves for nude mice in the tumor metastasis assay. Data are presented as the mean ± SD of three independent experiments. * P < 0.05

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