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Fig. 4 | Cell & Bioscience

Fig. 4

From: SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival

Fig. 4

SEPT2-K74R inhibited cell migration and invasion in vitro. A Overexpression of SEPT2-K74R inhibited migration of Huh7 cells (left panel) and SNU449 cells (right panel) with and without 25 mM sodium crotonate (NaCr) treatment. B Overexpression of SEPT2-K74R inhibited the invasion of Huh7 cells (left panel) and SNU449 cells (right panel) with and without 25 mM NaCr treatment. C Overexpression of SEPT2-K74R inhibited the migration of Huh7 cells (upper panel) and SNU449 cells (lower panel) with and without 25 mM NaCr treatment. The data are presented as the means ± SD. Ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (one-way ANOVA). NC, negative control; WT, wild type; 74R, SEPT2-K74R; NC-Cr, SEPT2-WT-Cr and K74R-Cr indicate NC, SEPT2-WT and SEPT2-K74R cells treated with 25 mM NaCr, respectively

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Cell & Bioscience

ISSN: 2045-3701

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