Fig. 4

EXOs from lipopolysaccharide (LPS)-stimulated RAW264.7 can cause kidney damage in vivo. a Trace analysis of the metabolism (in vivo) of DIR-labeled EXOs injected into C57BL/6 mice via the tail vein. b–d Western blot analysis of neutrophil gelatinase-associated lipocalin (NGAL) and vascular cell adhesion molecule-1 (VCAM-1) after RAW264.7 exosomes extraction and injection into mice. Data represent the mean ± SEM in independent experiments. ^*P < 0.05, ^**P < 0.01versus Con