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Fig. 2 | Cell & Bioscience

Fig. 2

From: Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury

Fig. 2

Macrophage infiltration increased and exosome (EXO) secretion increased in the lipopolysaccharide (LPS)-induced acute kidney injury (AKI) model. a, b Creatinine and urea nitrogen levels in LPS-induced AKI model after 12 and 16 h, respectively. c–e Neutrophil gelatinase-associated lipocalin (NGAL) and vascular cell adhesion molecule-1 (VCAM-1) expression in renal cortex by western blotting in LPS -induced AKI model. f Expression of macrophage marker, F4/80, was detected by immunohistochemistry in LPS-induced AKI. Scale bar ×100 and ×400. g CD63 expression in renal cortex EXOs of LPS-induced AKI model was detected by western blot. i CD63 was up-regulated in LPS-induced AKI. Scale bar ×400. Data represent the mean ± SEM for groups of 8 mice or independent experiments. *P < 0.05, **P < 0.01 versus Con

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