Fig. 1
From: AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation
The abundance of AMPK expression was positively correlated with the prognosis of MB. A Representative immunohistochemical staining of phosphorylated AMPK in normal cerebellar tissues (n = 3) and medulloblastoma tissues (n = 3). Scale bar, 20 μm. B Comparison of mRNA abundance of PRKAA1 in normal cerebella (n = 291) and medulloblastoma (n = 1350). Data from GSE124814. Comparison of two groups, ***P < 0.001. C Expression of PRKAA1 in four subgroups of MB samples from GSE124814 dataset. Comparison to normal, *P < 0.05, ***P < 0.001. D Kaplan–Meier analysis of PRKAA1 in different subtypes of medulloblastoma. Data from GSE85217. E TCGA figure showing mutations in selected genes. The figure panel was created using the cBioPortal for the MB data set available on the portal