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Fig. 3 | Cell & Bioscience

Fig. 3

From: Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification

Fig. 3

Decreased Piezo1 and enhanced methylation in the intestinal mucosa of WAS model mice. A Western blot of Piezo1, Suv39h1, Hdac3, GAPDH, H3K9me3 and T-H3 (Internal parameter for nuclear protein H3K9me3) in the mucosa of control and WAS mice. B Statistical analysis of protein expression in panel A. C Immunofluorescence for co-localization of AGR2 (label of goblet cells) and H3K9me3 in intestinal mucosa of control and WAS mice; bar length: 20 μm. D Immunofluorescence for co-localization of AGR2 (label of goblet cells) and Piezo1 in intestinal mucosa of control and WAS mice; bar length: 20 μm

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