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Fig. 3 | Cell & Bioscience

Fig. 3

From: Photobiomodulation improves the synapses and cognitive function and ameliorates epileptic seizure by inhibiting downregulation of Nlgn3

Fig. 3

PBM affects the number of synapses prior to kainic acid induced morphological changes of dendrites and neuronal population. A Representative images of PSD95 and MAP2 at 1, 2, and 3 h showed that 850 nm PBM protected PSD95 puncta against kainic acid-induced PSD loss after 3 h. The scale bars indicate 20 µm. B Bar graph shows significant changes in PSD puncta following treatment with 850 nm PBM at 3 h in presence of kainic acid as indicated. Data are expressed as the mean ± SEM; *p < 0.05 relative to 3 h kainic acid (two-way ANOVA with the Bonferroni test). C, D Quantification of neurite pruning and dendrite length per neuron based on MAP2 signals. There are no significantly difference after 850 nm PBM treated

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