Fig. 2

Annotation of scRNA-seq in early pregnancy loss. a UMAP of scRNA-seq data from the four early pregnancy loss groups A_SM, B_SM, C_RM, and D_ET. Each color presents a cell cluster of a different cell type. b Number of cells (shown in brackets) that have been sequenced for each cluster (color and number corresponding to the UMAP). c Percentage (%) of cells (Y axis) in each cluster for individual placental samples in groups A, B, C, and D (X axis). CTB cytotrophoblasts, VCT villous cytotrophoblasts, STB syncytiotrophoblasts, EVT extravillous trophoblasts, HB Hofbauer (fetal macrophage) cells, FB fibroblasts, MO monocytes, Plasma plasma cells, Blood NK CD16⁺ blood natural killer CD16⁺ cells, DEC decidual cells, dM decidual macrophages, dNK decidual natural killer cells, dS decidual stromal cells, DC dendritic cells, PV perivascular cells, Epi epithelial glandular cells, Endo M endothelial maternal cells, Endo F endothelial fetal cells, Endo L endothelial lymphatic cells.