Fig. 3

Gene expression analysis of liver tissue in CLP mice and WT mice. A Hierarchical clustered heatmap of differentially expressed genes (DEGs) in liver tissues between CLP mice and WT mice, n = 3 log2 FC > 1, Q value < 0.05. B Kyoto Encyclopedia of Genes and Genomes enrichment analysis(KEGG pathway)was adopted to identify the most significantly altered signaling pathways in liver tissues of CLP mice, n = 3. C Construction of protein-protein interaction (PPI) regulatory network based on DEGs. D, E Network of KEGG pathway based on similarity of their gene expression profiles. F, G SLC7A11 and NCOA4 of mouse liver tissues was stained by Immunohistochemical