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Fig. 2 | Cell & Bioscience

Fig. 2

From: YAP1 protects against septic liver injury via ferroptosis resistance

Fig. 2

YAP1 deficiency aggravated CLP-induced ferroptosis and ferritinophagy in liver tissues. A Representative images showed by TEM. The red arrow indicates representative mitochondria in YAP1fl/fl or YAP1fl/fl Alb-Cre mice liver treated by CLP or not. B, C Fluorescent analysis showed representative images of colocalization ferritin (green) with tissues expressed LC3 (red) and quantification fluorescence intensity of LC3, n = 6. D, E Immunobloting detection of the expression contents of GPX4, ACSL4, SLC7A11, LC3 (I, II), FTH1, and NCOA4 in mice with indicated treatment, n = 6. Data are expressed as mean ± SD of three replicates. *p < 0.05, **p < 0.01, ***p < 0.001

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