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Fig. 2 | Cell & Bioscience

Fig. 2

From: Aberrant methylation of Serpine1 mediates lung injury in neonatal mice prenatally exposed to intrauterine inflammation

Fig. 2

Intranasal delivery of Serpine1 siRNA reversed lung injury induced by IUI. A The mRNA expression of Serpine1 analysed using RT-qPCR in lung tissues of neonatal mice. B, C Serpine1 expression analysed using western blot in lung tissues of neonatal mice. C Immunofluorescence detection of Serpine1 in lung tissues of neonatal mice. (green, DAPI: blue). Scale bars, 100 μm. E–G Histological examination of siRNA-treated neonatal mouse lungs. The lung tissue was stained with hematoxylin and eosin. The alveolar number and alveolar size were quantified. Scale bars, 200 μm. Data show mean ± SEM; Data was analysed using unpaired t-tests

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