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Table 4 CD8+ T cell FlowSOM (w/ PD-L1) cluster proportions in healthy volunteers, mild AD, and moderate AD patients

From: A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

 

Median value

Independent-Samples Mann–Whitney U Test Significance

Subject

Healthy volunteer

Mild AD

Moderate AD

Hv vs. Mild

Mild vs. Moderate

Hv vs. Moderate

Pop0 (%)

10.15

8.065

16.8

0.551

0.073

0.294

Pop1 (%)

39.8

30.25

27.2

0.047*

0.875

0.115

Pop2 (%)

0.59

0.415

0.135

0.336

0.263

0.07

Pop3 (%)

0.375

0.24

0.2

0.4894

0.635

0.367

Pop4 (%)

2.98

2.95

1.435

0.586

0.031*

0.154

Pop5 (%)

18.9

24.4

19

0.027*

0.093

1

Pop6 (%)

12.9

14.15

15.3

1

0.368

0.541

Pop7 (%)

6.795

12.6

14.25

0.087

0.792

0.115

  1. AD Alzheimer’s disease, Pop FlowSOM population, Hv Healthy volunteers
  2. *p < 0.05