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Table 3 CD8+ T cell FlowSOM (w/ PD-1) cluster proportions in healthy volunteers, mild AD, and moderate AD patients

From: A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

 

Median value

Independent-Samples Mann–Whitney U Test Significance

Subject

Healthy volunteer

Mild AD

Moderate AD

Hv vs. Mild

Mild vs. Moderate

Hv vs. Moderate

Pop0 (%)

12.1

5.39

10.495

0.165

0.263

0.693

Pop1 (%)

11.3

15.45

16.35

0.363

0.875

0.693

Pop2 (%)

23.35

22.55

23.6

0.856

0.875

0.914

Pop3 (%)

18.85

25.9

24.8

0.047*

0.713

0.329

Pop4 (%)

21.1

17.05

17.7

0.241

0.562

0.494

Pop5 (%)

4.165

6.235

3.48

0.586

0.118

0.294

Pop6 (%)

0.515

0.58

0.24

0.551

0.313

0.154

Pop7 (%)

2.505

2.935

1.22

0.897

0.093

0.04*

  1. AD Alzheimer’s disease, Pop FlowSOM population, Hv Healthy volunteers
  2. *p < 0.05