Fig. 2
From: Reliable assessment of telomere maintenance mechanisms in neuroblastoma
Telomere content and telomere restriction fragment analysis in TMM subgroups. A Telomere content (TC) calculated from WGS data, displayed as tumor/normal ratio, in telomere maintenance defined subgroups. Mean telomere content: TMM[−], 0.87; ALT[+], 6.39; TEL[+], 0.96. Kruskal–Wallis test and Dunn’s multiple comparison test were used for statistical analysis; ambiguous cases were excluded. Whiskers are limited to 1.5 × interquartile range. B Telomere restriction fragment (TRF) analysis, displayed in kilobase pairs (kbp), in telomere maintenance defined subgroups. Mean telomere length: TMM[−], 8.39; ALT[+], 10.66; TEL[+], 6.36. Kruskal–Wallis test and Dunn’s multiple comparison test were used for statistical analysis; ambiguous cases were excluded. Whiskers are limited to 1.5 × interquartile range. C Correlation analysis of TRF and TC in neuroblastoma samples (n = 36). Ambiguous cases were excluded from calculation of Pearson correlation