Fig. 3
From: Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer
Examination of NEPC specificity for the chimeric RNAs. A Gel images of qRT- PCR products of SPSB4-PXYLP1 and RIPPLY2-CYB5R4, which are not exclusively expressed in NEPC cell lines. B Quantitative analysis of SPSB4-PXYLP1 and RIPPLY2-CYB5R4 in different cell lines. C Validation of 13 NEPC specific chimeric RNAs in NCI-H660 and LASCPC-01. Red arrows point to correct products. Yellow arrow points to a non-specific product in LASCPC-01. D The schematic diagrams of four chimeric RNAs. Blocks represent exons. Black lines represent introns or intergenic regions. Red lines (arrows) represent junction sites. ****p < 0.0001