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Fig. 7 | Cell & Bioscience

Fig. 7

From: PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

Fig. 7

Sevoflurane inducing PND with neuroinflammation in the cortex and hippocampus. A, Sevoflurane up-regulated IL-6 in the hippocampus (n = 4). B, Sevoflurane up-regulated TNF-α in the hippocampus (n = 4). C, Sevoflurane up-regulated IL-1β in the hippocampus (n = 4). D, Sevoflurane up-regulated IL-6 in the cortex (n = 4). E, Sevoflurane up-regulated TNF-α in the cortex (n = 4). F, Sevoflurane up-regulated IL-1β in the cortex (n = 4). G, HE staining of cortex and hippocampus. Arrows indicate neurons. Triangles indicate inflammatory cells. Data are shown as mean ± SD. *P < 0.05 or **P < 0.01.

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