Skip to main content
Fig. 2 | Cell & Bioscience

Fig. 2

From: TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation

Fig. 2

TRIM22 inhibits ZIKV infection in vitro. a–c TRIM22 was over expressed in A549 cells, the cells were subsequently infected with ZIKV at MOI = 0.1, 12 h post transfection, ZIKV load in cells lysates (a) and culture supernatants (b) were measured by qRT-PCR or plaque assay (c). d Western blot analysis of TRIM22 overexpressed A549 cells which were infected with ZIKV. e, f Wild type and TRIM22 gene knockout A549 cells were infected with ZIKV at MOI = 0.01. qRT-PCR was performed to detect the ZIKV RNA in cell lysates (e) and culture supernatant (f). Plaque assay and qRT-PCR data (a–c, e and f) are means ± SEM from three independent experiments. **P < 0.05, **P < 0.01 and ***P < 0.001 by Student’s t test

Back to article page