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Fig. 7 | Cell & Bioscience

Fig. 7

From: Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits

Fig. 7

Long-term effects of perinatal intermittent hypoxia on spatial learning in adult mice. A–C. Measurement of the latency to find the platform (A), of the freezing time (B), and of the path efficiency (C) during the cue sessions of the Morris water-maze test performed in 14 control (N) and 10 hypoxic (IH) mice between P56 and P60. D Measurement of the time spent (left) and distance travelled (right) in the target quadrant during the probe session of the Morris water-maze test, performed on control (N) and hypoxic (IH) P60 mice. E Representative pattern of the time spent in the target quadrant during the probe session of the Morris water-maze test for one control mouse (N) and one hypoxic mouse (IH) at P60. Red and yellow regions represent areas of high occupancy; green and blue represent areas of low occupancy. The total number of animals in each experimental group is indicated under the boxplots in D and exact p-values are indicated above. IH: intermittent hypoxia condition; N: normoxia condition; Px: postnatal day x

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