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Fig. 5 | Cell & Bioscience

Fig. 5

From: Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits

Fig. 5

Effects of perinatal intermittent hypoxia on weight and behavioral development in young mice. A, B Measurement of the latency to turn in the righting reflex test (A) and to fall in the grasping reflex test (B) between P2 and P11 in 18 control (N) and 15 hypoxic (IH) mice. C Measurement of the weight gain of control (N) and hypoxic (IH) mice between P2 and P21 (N = 22, IH = 18 from P2 to P11—N = 4, IH = 3 from P12 to P21). Top-left insert: baseline control of P0 weight averaged from the total litter weight. D Measurement of the muscular strength using the forelimb grip strength test in control (N) and hypoxic (IH) P21 mice (3 technical replicates per animal). The total number of animals in each experimental group is indicated under the boxplots and represented by diamond shapes, while the transparent dots indicate individual data points. Exact p-values are indicated above the plot. IH: intermittent hypoxia condition; N: normoxia condition; Px: postnatal day x

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Cell & Bioscience

ISSN: 2045-3701

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