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Table 1 Baseline characteristics in 1606 CAD patients

From: Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease

Characteristics

Discovery cohort (n = 1040)

Multicenter validation cohort (n = 566)

 

Demographic data

 

 Age

63.03 ± 10.04

62.29 ± 10.18

 

 Sex (male)

828 (79.62)

419 (74.16)

 

 BMI, kg/m2

24.28 ± 4.79

24.06 ± 3.38

 

 SBP, mm Hg

130.66 ± 18.89

133.04 ± 20.29

 

 DBP, mm Hg

76.19 ± 11.03

76.46 ± 12.05

 

 Current smoking

294 (28.52)

160 (28.73)

 

 Family of CVD

29 (2.79)

–

 

Comorbidities

 

 Arrhythmia

92 (8.86)

51 (9.17)

 

 DM

286 (27.55)

164 (29.39)

 

 HyperT

627 (60.35)

340 (60.93)

 

 Dyslipidemia

729 (72.54)

400 (74.07)

 

Biomedical measurements

 

 ALT, U/L

27.41 ± 13.18

27.65 ± 24.56

 

 AST, U/L

26.64 ± 10.62

32.12 ± 55.48

 

 eGFR, mL/min/1.73 m2

94.32 ± 73.69

91.37 ± 110.84

 

 GLUC, mmol/L

6.74 ± 2.73

6.21 ± 3.82

 

 CHOL, mmol/L

4.28 ± 1.12

4.29 ± 1.77

 

 LDLC, mmol/L

2.58 ± 0.93

2.7 ± 1.00

 

 HDLC, mmol/L

0.97 ± 0.26

0.99 ± 0.25

 

 TRIG, mmol/L

1.62 ± 1.14

1.85 ± 1.85

 

 CKMB, U/L

7.48 ± 5.92

19.37 ± 52.83

 

 proBNP, pg/mL

774.51 ± 1597.35

1299.46 ± 4922.09

 

Medications

 

 BB

929 (89.5)

477 (84.57)

 

 ACEI

660 (63.58)

286 (50.71)

 

 CCB

295 (28.42)

165 (30.05)

 

 PPI

506 (48.75)

380 (67.26)

 

SYNTAX score

16.43 ± 10.74

16.45 ± 13.09

 

LVEF, %

60.1 ± 11.54

59.43 ± 11.63

 

LVMI, g/m2

122.13 ± 36.05

116.54 ± 35.08

 
  1. Data are number (%) or mean ± SD when appropriate
  2. SD standard deviation, BMI body mass index, SBP systolic blood pressure, CVD cardiovascular disease, DM diabetes, HyperT hypertension, ALT alanine aminotransferase, AST aspartate aminotransferase, eGFR estimated glomerular filtration rate, GLUC glucose, CHOL cholesterol, LDLC low-density lipoprotein cholesterol, HDLC high-density lipoprotein cholesterol, TRIG triglyceride, CKMB creatine kinase MB, proBNP N-terminal pro brain natriuretic peptide, BB β-blockers, ACEI angiotensin converting enzyme inhibitors, CCB calcium channel blockers, PPI proton pump inhibitors, SYNTAX score Synergy between PCI with TAXUS and Cardiac Surgery score, LVEF left ventricular ejection fraction, LVMI left ventricular mass index