Fig. 3

Correlation network of metabolic signatures and clinical factors, and metabolomic association with LV remodeling. A Correlation network of the metabolic signatures for death risk in the discovery cohort and traditional clinical factors by Spearman correlations with distant nodes of |rho|> 0.1 for clinical factors and |rho|> 0.2 for metabolites, P < 0.01, the rho and P-value were provided in Additional file 1: Table S6. Volcano plot presentation of univariate association of metabolites with LVEF (B) and LVMI (C) in a linear regression model. Metabolites with P < 0.05 are labeled (above the red dotted line), P-value cutoff equivalent to FDR < 0.05 are labeled (above the green dotted line), abbreviations are as Table 1