Fig. 4
From: CDKN2AIP is critical for spermiogenesis and germ cell development
Identification of the Related genes and proteins affected by Cdkn2aip mutation using RNA-Seq and IP-MS. A Venn diagram showing the number of unique transcript isoforms detected in Cdkn2aip+/+ (762) and Cdkn2aip−/− (985) testes. B RNA-Seq analysis of differentially expressed genes from Cdkn2aip+/+ and Cdkn2aip−/− testes. C The GO enrichment ratio for identified genes was performed on RNA Seq data from Cdkn2aip+/+ and Cdkn2aip−/− testis. E Results of function annotation and gene ontology (GO) term enrichment analyses of CDKN2AIP-interacting proteins by IP-MS. F A representative gel image showing bands proteins immunoprecipitated by CDKN2AIP antibody in the Cdkn2aip+/+ and Cdkn2aip−/− testis (left), and the list of partial differential proteins form the Cdkn2aip+/+ and Cdkn2aip−/− testis by IP-MS (right)