GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis

Table 2 The relationship between GREM1/BMP and TGF-β1/PPP2R3A

Pathway	Gene
Mesenchymal cell differentiation	Bmp2\|Fn1\|Tgfb1\|Grem1
Regulation of the cellular response to growth factor stimulus	Bmp2\|Tgfb1\|Grem1
Extracellular matrix organization	Bmp2\|Fn1\|Tgfb1\|Grem1
Regulation of the Wnt signaling pathway	Bmp2\|Tgfb1\|Grem1\|Ppp2r3a
Wnt signaling pathway	Bmp2\|Tgfb1\|Grem1\|Ppp2r3a
Cell–cell signaling by Wnt	Bmp2\|Tgfb1\|Grem1\|Ppp2r3a
Positive regulation of the Wnt signaling pathway	Bmp2\|Tgfb1\|Ppp2r3a
Cell surface receptor signaling pathway involved in cell–cell signaling	Bmp2\|Tgfb1\|Grem1\|Ppp2r3a
Regulation of the MAPK cascade	Bmp2\|Fn1\|Tgfb1\|Grem1
Negative regulation of cell population proliferation	Bmp2\|Tgfb1\|Grem1
Regulation of cell adhesion	Bmp2\|Fn1\|Tgfb1\|Grem1

Shows the related signaling pathways in which GREM1, BMP, TGF-β1, PPP2R3A and FN1 were enriched