Fig. 2
From: GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis
Correlation analysis of fibroblast subtypes. A Percentage of each fibroblast subtype among the total fibroblasts in different groups (saline and silica groups) at different time points (7 and 56 days). B Proportion of grem1high fibroblasts in different groups at different time points. C Distribution of each subtype of fibroblasts in the saline and silica groups at 7 and 56 days. D The quasi-chronological analysis shows the status of the whole fibroblast population at each node of transdifferentiation. E Status of each subtype of fibroblasts at the node of transdifferentiation. F The lesion area contains a large number of grem1high fibroblasts. G Based on the expression of the top 10 genes with multiple changes in Cluster 5 compared with other subtypes, the numbers 1–10 correspond to the 10 genes in the left column, and the bubble size represents the size of multiple changes. grem1 is only expressed in Cluster 5. H Venn diagram showing the number of identical genes expressed in the different subtypes