Table 2 CSF concentrations of inflammatory parameters and NfL
From: Tick-borne encephalitis affects sleep–wake behavior and locomotion in infant rats
Cytokine | Timepoint | Control [pg/mL] | Infection [pg/mL] | p-Value |
|---|---|---|---|---|
RANTES | Day 4 | 16.79 (n = 14) | 503.18 (n = 20) | 0.0033 |
Day 9 | 14.54 (n = 13) | 80.31 (n = 23) | 0.0062 | |
Day 21 | 23.98 (n = 13) | 45.39 (n = 18) | 0.0216 | |
IL-6 | Day 4 | 236.94 (n = 15) | 1363.22 (n = 26) | 0.0082 |
Day 9 | 145.73 (n = 15) | 142.99 (n = 28) | 0.1816 | |
Day 21 | 131.69 (n = 13) | 120.02 (n = 18) | 0.6472 | |
IFN-γ | Day 4 | 68.13 (n = 15) | 361.22 (n = 26) | 0.0281 |
Day 9 | 39.68 (n = 15) | 63.23 (n = 28) | 0.1396 | |
Day 21 | 49.07 (n = 13) | 22.25 (n = 18) | 0.7477 | |
MCP-1 | Day 4 | 224.61 (n = 15) | 697.12 (n = 26) | 0.0164 |
Day 9 | 29.04 (n = 14) | 306.09 (n = 28) | 0.0076 | |
Day 21 | 204.48 (n = 13) | 460.53 (n = 18) | 0.5255 | |
IP-10 | Day 4 | 140.57 (n = 14) | 2188.54 (n = 22) | 0.0001 |
Day 9 | 131.62 (n = 14) | 1533.96 (n = 26) | 0.0003 | |
Day 21 | 279.62 (n = 13) | 1095.21 (n = 18) | 0.0034 | |
NfL | Day 4 | 472.77 (n = 13) | 401.47 (n = 19) | 0.878 |
Day 9 | 633.50 (n = 14) | 1065.21 (n = 19) | 0.0083 | |
Day 21 | 346.9 (n = 10) | 392.7 (n = 10) | 0.6232 |