Fig. 6
From: Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer
Oxy186 inhibits expression of many genes involved in the basal cell carcinoma pathway. A. Heat map of Basal Cell Carcinoma pathway. Gene expression in the heat map is standardized by row. B. RT-qPCR showed that Oxy186 significantly inhibited GLI1, GLI2 and PTCH2 expression in xenografts, whereas the effect of Oxy210 was not statistically significant. Data reported as the mean (n = 6) ± SD (* p < 0.05; ** p < 0.02)