Fig.3

cGAS is critical for Alu RNA-induced cell death. a Annexin V/PI analysis by flow cytometry of WT and CGAS^−/− ARPE-19 cells transfected with Alu RNA (4 μg mL⁻¹) for 48 h or non-transfected (Ctrl). b The percentage of dead cells in (a) was quantified. Data are mean ± s.e.m. of three independent experiments, *P < 0.05, two-tailed t-test (b)