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Fig. 4 | Cell & Bioscience

Fig. 4

From: LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer

Fig. 4

CRLM1–chromatin interaction and its effect on gene expression. A Percentage of CRLM1-bound peaks in different genomic regions. B Percentage of CRLM1-bound peaks in 5 kb of TSS upstream was compared to that in gene body exclude intron region. C The top 10 representative GO Biological Process terms of all CRLM1 binding genes. D Venn diagram of CRLM1 binding genes by ChIRP-DNA and differentially expressed genes upon CRLM1-OE. E The unsupervised hierarchical clustering heatmap showing the expression level of CRLM1-bound genes by ChIRP-DNA from CRLM1-OE and Ctrl samples. F The top 10 representative GO Biological Process terms of CRLM1-bound genes which were regulated by CRLM1-OE (genes in black box of D). G Boxplots showing expression status of six CRLM1-bound genes which were regulated by CRLM1-OE genes from CRLM1-OE and Ctrl samples. H Boxplots showing expression status of six CRLM1-bound genes which were regulated by CRLM1-OE genes from 54 GEO samples

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