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Fig. 3 | Cell & Bioscience

Fig. 3

From: LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer

Fig. 3

CRLM1-OE converts the CRC cell transcriptome to the metastasis state. A The number of DEGs among different groups. The number of up-regulated and down-regulated DE lncRNAs was showed in bar plot. “overlap” indicates the co-regulated genes between CRLM1 vs Anti and CRLM1 vs Ctrl. B, C The top 10 representative GO Biological Process terms of up- (B) and down-regulated genes (C) between CRLM1-OE and Ctrl. D Boxplots showing expression status of 4 differentially expressed TFs comparing CRLM1-OE with Ctrl samples. E Boxplots showing expression status of 10 EMT-related genes comparing CRLM1-OE with Ctrl samples. F Venn diagram of differentially expressed genes upon CRLM1-OE, metastasis-related genes from HCMDB database and CRLM1 co-expressed genes

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Cell & Bioscience

ISSN: 2045-3701

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