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Table 1 Relationship between clinicopathologic parameters and Siglec-15 and Beclin-1 expression in human osteosarcoma tissues

From: Siglec-15-induced autophagy promotes invasion and metastasis of human osteosarcoma cells by activating the epithelial–mesenchymal transition and Beclin-1/ATG14 pathway

Variables

N (52)

Siglec-15 expression

Beclin-1 expression

+

P

+

P

Age

 ≤ 25

17

7

10

0.257

11

6

0.622

 > 25

35

9

26

 

25

10

 

Sex

 Male

33

11

22

0.598

23

10

0.924

 Female

19

5

14

 

13

6

 

Size (cm)

 ≤ 5

15

5

10

1.000

13

2

0.161

 > 5

37

11

26

 

23

14

 

Histological classification

 Osteoblastic

20

5

15

0.610

17

3

0.149

 Chondroblastic

20

6

14

 

12

8

 

 Others

12

5

7

 

7

5

 

Main tumor location

Limb bone

38

13

25

0.795

27

11

0.892

 Spine

6

1

5

 

4

2

 

 Pelvis

8

2

6

 

5

3

 

Lung metastasis

 Yes

21

11

10

0.005

18

3

0.034

 No

31

5

26

 

18

13