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Table 1 Relationship between clinicopathologic parameters and Siglec-15 and Beclin-1 expression in human osteosarcoma tissues

From: Siglec-15-induced autophagy promotes invasion and metastasis of human osteosarcoma cells by activating the epithelial–mesenchymal transition and Beclin-1/ATG14 pathway

Variables N (52) Siglec-15 expression Beclin-1 expression
+ P + P
Age
 ≤ 25 17 7 10 0.257 11 6 0.622
 > 25 35 9 26   25 10  
Sex
 Male 33 11 22 0.598 23 10 0.924
 Female 19 5 14   13 6  
Size (cm)
 ≤ 5 15 5 10 1.000 13 2 0.161
 > 5 37 11 26   23 14  
Histological classification
 Osteoblastic 20 5 15 0.610 17 3 0.149
 Chondroblastic 20 6 14   12 8  
 Others 12 5 7   7 5  
Main tumor location
Limb bone 38 13 25 0.795 27 11 0.892
 Spine 6 1 5   4 2  
 Pelvis 8 2 6   5 3  
Lung metastasis
 Yes 21 11 10 0.005 18 3 0.034
 No 31 5 26   18 13