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Fig. 1 | Cell & Bioscience

Fig. 1

From: Siglec-15-induced autophagy promotes invasion and metastasis of human osteosarcoma cells by activating the epithelial–mesenchymal transition and Beclin-1/ATG14 pathway

Fig. 1

Siglec-15 and Beclin-1 expression is closely related to lung metastases of osteosarcoma. a Contrasting with those without lung metastases, osteosarcoma patients with lung metastasis had higher expression of Siglec-15 and Beclin-1 in the primary tumor using immunohistochemistry. b The immunohistochemistry results indicated that significantly higher expression levels of Siglec-15 and Beclin-1 were detected in lung metastases. c Siglec-15 and Beclin-1 expression levels show a positive correlation in lung metastases. Representative immunohistochemical images are shown at ×200 and ×400 magnification. Data are presented as the mean ± SD. *P < 0.05

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Cell & Bioscience

ISSN: 2045-3701

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