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Fig. 1 | Cell & Bioscience

Fig. 1

From: Human skin dermis-derived fibroblasts are a kind of functional mesenchymal stromal cells: judgements from surface markers, biological characteristics, to therapeutic efficacy

Fig. 1

Morphology and surface marker expression profiles of UC-MSCs and fibroblasts. A UC-MSCs and three types of fibroblasts at passage 3 shared higly similar long-spindle morphologyunder a microscope. Bar scale = 200 μm. B, C The quantification of length and width of UC-MSCs and fibroblasts. D Flow cytometry was used to detect the surface marker expressions of UC-MSCs and fibroblasts. All types of cells negatively expressed CD14, CD19, CD34, CD45, and HLA-DR, while positively expressed CD73, CD90, and CD105. E The quantification of the surface marker expressions of indicated cells. F, G Expression distribution and level of Vimentin, α-SMA, and S100A4 in UC-MSCs and fibroblasts were tested by immunofluorescence and WB. Bar scale = 100 μm. (*p < 0.05, **p < 0.01, and ***p < 0.001)

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