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Table 5 Overview of prognostic, diagnostic and clinicopathological significance of circRNAs in pancreatic cancer plasmas

From: Biological functions, mechanisms, and clinical significance of circular RNA in pancreatic cancer: a promising rising star

No

Circ

Expression

Cut-off

Detect

Clinical significance

AUC

Sensitivity

Specificity

Survival

Prognostic biomarker

Reference

1

0002130/0000896/0101692/0005882/0001250/0000128

Up

 

qRT-PCR

      

31,605,569

2

0103896/0006662/0035432/0094190

Down

 

qRT-PCR

      

31,605,569

3

0,001,013

Up

 

qRT-PCR

      

33,563,550

4

chr12:74,678,804–74,700,449

Up

 

qRT-PCR

      

32,879,441

5

0006988

Up

 

qRT-PCR

CA19-9 level, Vessel invasion, Lymphatic invasion, Distance metastasis, TNM stage

0.67

0.5738

0.7049

  

29,307,994

6

0000677

Up

 

qRT-PCR

 

0.716

0.6276

0.7429

  

33,413,045

7

0036627

 

MEL

qRT-PCR

Duodenal invasion, Vessel invasion, T stage, TNM stage

   

OS

+

29,709,702

8

IARS

Up

 

qRT-PCR

Exosomes from patients with or without metastasis

     

30,064,461

9

chr14:101,402,109–101,464,448/chr4:52,729,603–52,780,244

Up in non-GEM-responsive

 

qRT-PCR

      

29,922,161

  1. MEL: Median Expression Level; AUC: Area Under the Curve; OS: Overall Survival