Fig. 4
From: IL-1R/C3aR signaling regulates synaptic pruning in the prefrontal cortex of depression
The dynamic change of C3/C3aR in the prefrontal cortex in a 4-week chronic stress procedure. The dynamic change of sucrose preference (A), C3 (B) and C3aR (C) levels in mice. Representative photographs of C3(green) (D) and the statistical results (E). Representative photographs of Iba1(green)/C3aR(red)/DAPI(blue) (F). The dynamic change of microglial activation (G) and C3aR expression (H). Data were obtained from 5–10 samples per group. #P < 0.05 and ##P < 0.01 versus the Control-vehicle group