Skip to main content

Table 2 Strategies to target TAMs in combination with other anticancer therapies

From: Targeting tumor-associated macrophages for cancer treatment

Therapy strategies

Drug combination

Cancer type

Refs.

TAMs-chemotherapy

CSF1R blocking mAb + bortezomib

Multiple myeloma

[77]

 

CSF1R blocking mAb + melphalan

  
 

PF-04136309 + FOLFIRINOX

Pancreatic cancer

[69]

 

Emactuzumab + paclitaxel

Advanced/metastatic solid tumor

[96]

 

R848 + oxaliplatin

Colorectal cancer

[80]

TAMs-immunotherapy

CCR2i + anti-PD-1

Cutaneous t-cell lymphoma

[106]

 

CCX872 + anti-PD-1

Glioblastoma

[71]

 

Lefitolimod + anti-PD-1

Melanoma

[79]

TAMs-nanotechnology

R848 + β-cyclodextrin

Colorectal cancer

[109]

 

MiR155 + LDH

Colorectal cancer

[112]