From: Targeting tumor-associated macrophages for cancer treatment
Therapy strategies | Drug combination | Cancer type | Refs. |
---|---|---|---|
TAMs-chemotherapy | CSF1R blocking mAb + bortezomib | Multiple myeloma | [77] |
 | CSF1R blocking mAb + melphalan |  |  |
 | PF-04136309 + FOLFIRINOX | Pancreatic cancer | [69] |
 | Emactuzumab + paclitaxel | Advanced/metastatic solid tumor | [96] |
 | R848 + oxaliplatin | Colorectal cancer | [80] |
TAMs-immunotherapy | CCR2i + anti-PD-1 | Cutaneous t-cell lymphoma | [106] |
 | CCX872 + anti-PD-1 | Glioblastoma | [71] |
 | Lefitolimod + anti-PD-1 | Melanoma | [79] |
TAMs-nanotechnology | R848 + β-cyclodextrin | Colorectal cancer | [109] |
 | MiR155 + LDH | Colorectal cancer | [112] |