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Fig. 3 | Cell & Bioscience

Fig. 3

From: Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection

Fig. 3

HDAC3 deacetylases the histones on the promoters of cathepsins. A Heat map representation of correlation between each biological replicates of Vector and Hdac3−/− RAW264.7 cells for H3K27ac. B Distribution of H3K27ac-binding loci relative to transcriptional start site (TSS). C H3K27ac signals in Vector and Hdac3−/− RAW264.7 at TSS. D Genome-wide distribution of H3K27ac ChIP-seq peaks in RAW264.7 cells. E–J The Integrative Genomics Viewers (IGVs) for H3K27ac occupied on the promoter of Ctsa, Ctsb, Ctsd, Ctsl, Ctss and Ctsz. Each CHIPseq data of histone marks were merged from three individual replicates

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Cell & Bioscience

ISSN: 2045-3701

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