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Fig. 1 | Cell & Bioscience

Fig. 1

From: Mosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men

Fig. 1

Age-related macular degeneration (AMD) and mosaic Loss of Y-chromosome (mLOY) in ageing. A Development of monocyte-macrophage system associated mLOY from bone marrow to peripheral blood; B Circulating mLOY leukocyte targeting on retina leads to AMD vision. ONL, outer nuclear layer; ISP, inner segment, photoreceptor; OSP, outer segment, photoreceptor; RPE, retinal pigment epithelium; BrM, Bruch’s membrane

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