Fig. 2
From: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing
Histopathology of livers from E16 mice in acute phase. a Hematoxylin/eosin-stained sections of liver samples from representative WT and E16 mice. Bar = 100 μm. b Cell nuclei in DAPI-stained liver sections. c Nuclei counted in the micrographs in b and their distribution according to size, in WT vs. E16 liver samples. Mean nuclear size differs between genotypes, as assessed by unpaired t-test (p < 0.05). d Anti-DIDO3 fluorescent staining of liver sections in stitched 2 × 2 confocal tiles. Bar = 100 μm. e Anti-PCNA fluorescent staining of liver sections. Bar = 100 μm. f Anti-glutamine synthetase fluorescent staining of liver sections. Bar = 800 μm