Fig. 1
From: The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context
High expression of ATF2 in GC is associated with poor prognosis and chemotherapy response. A Immunohistochemistry staining was performed to evaluate the expression and location of ATF2 in human gastric cancer tissues. The original magnification is 200 ×. B Gene status of ATF2 including mutations (green), amplification (red), and deletions (blue) in GC tissue (n = 434) were analyzed using cBioportal software. C Overall survival of GC patients with ATF2-low or -high expression using TCGA database. D Overall survival of ATF2 low or -high expression group in GC patients without chemotherapy. E Overall survival of ATF2-low or ATF2-high expression group in GC patients with chemotherapy. F Overall survival of ATF2-low or ATF2-high expression group in GC patients with chemotherapy using GSE26253 dataset. Kaplan-Meier and Log-rank analysis is used, p value < 0.05 is considered statistically significant