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Fig. 1 | Cell & Bioscience

Fig. 1

From: Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma

Fig. 1

Expression pattern of KMT2D in patients with OSCC. A Representative immunohistochemical staining of KMT2D in normal mucosa and primary OSCC tissue of KMT2D(+) and KMT2D(−). (scale bars = 100 μm). B Quantification analysis of immunohistochemical histoscore of KMT2D among normal mucosa and OSCC. C KMT2D expression levels in OSCC tissues from different pathological grades. D KMT2D expression levels in OSCC tissues from different tumor sizes. E KMT2D mRNA expression levels of paired normal mucosa and OSCC from TCGA datasets. F KMT2D protein expression levels in different cell lines. G KMT2D protein expression in human OSCC tissues and adjacent normal mucosa from the same patient. Results are representative of at least three independent experiments (*p < 0.05, **p < 0.01). Data are presented as means ± SD. OSCC, oral squamous cell carcinoma; SD standard deviation, ns no significant, KMT2D(+) KMT2D positive, KMT2D(−) KMT2D negative

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