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Fig. 2 | Cell & Bioscience

Fig. 2

From: Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design

Fig. 2

a Superimposition of the structures of ILHV helicase and the DENV helicase (PDB: 2JLQ). b Superimposition of the structures of ILHV helicase and DENV helicase in complex with AMPPNP (PDB:2JLR). c The structural comparison of the DENV helicase (PDB: 2JLQ) and DENV-helicase-AMPPNP complex (PDB:2JLR). d Comparison of motif I, II, and VI in the helicases of 8 flavivirus which are colored in indicated color codes. e Sequence alignment of ILHV helicase P-loop with other flavivirus helicases. f Structural superimposition of the P-loop of ILHV helicase with other flavivirus helicases

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