Fig. 6
From: Rebuilding hippocampus neural circuit with hADSC-derived neuron cells for treating ischemic stroke
hADSC-NC terminal differentiation and brain vasculature rebuilding in the MCAO mouse hippocampus. The minus hADSC-NCs express the microglial cell marker Iba1 and the blood vessel marker CD31 in 3 areas of the hippocampus: A for CA1, B for CA2 and C for CA3. D shows the statistical analysis of the hADSC-NC distribution, the Iba1-positive percentage and the CD31-positive percentage in CA1, CA2 and CA3. E shows the electrophysiological properties of GFP-positive hADSC-NCs in live hippocampal slices. a Representative image of GFP-positive hADSC-NC-derived neurons during patch-clamp recording. b Action potentials could be elicited by a current injection. c Spontaneous IPSCs were recorded in patched neurons and blocked by 50 μM bicuculine. n = 7/8, Scale bar = 25 μm