Fig. 5
From: Rebuilding hippocampus neural circuit with hADSC-derived neuron cells for treating ischemic stroke
Characterization of hADSC-NCs in various MCAO mouse brain regions. A Shows the cell apoptosis marker cleaved Caspase 3. B Shows the negative expression of cleaved Caspase 3 in GFP-positive hADSC-NCs in the cortex. C Shows that the transplanted hADSC-NCs express cleaved Caspase 3, integrate well into the hippocampal tissue, and exhibit a healthy and complex neuron morphology. D, E Show similar cell survival, integration and neuron differentiation in the mouse striatum and hypothalamus. F Shows the statistical analysis of the hADSC-NC distribution, Caspase 3 positive percentage and GFP/Caspase 3 double-positive percentage. n = 5, Scale bar = 50 μm in B–D, scale bar = 25 μm in E