Fig. 4
From: MIR210HG promotes breast cancer progression by IGF2BP1 mediated m6A modification
miR-210 mediates MIR210HG function. A and B Unpaired and paired analysis of miR-210 expression in TCGA-BRCA. In unpaired analysis, 1109 tumor samples and 113 normal samples were included. In paired analysis, 112 tumor samples and 112 normal samples were included. C Overall survival rate and distant metastasis free survival rate of breast cancer patients with different miR-210 expression level were analyzed based on TCGA-BRCA dataset. High miR-210 expression was indicated as a red line and low miR-210 expression was indicated as a blue line. D Pearson correlation analysis between MIR210HG expression and miR-210 expression in breast cancer patients. E q-PCR analysis of miR-210 expression in four indicated breast cancer cell lines compared to 76 N-F2V cell. F q-PCR analysis of miR-210 expression in breast cancer tissues compared to adjacent tissues from 10 patients. G q-PCR analysis on miR-210 expression in MCF-7MIR210HG−OV and 231-7MIR210HG−OV cells with miR-210 inhibitor treatment. H proliferation rate was analyzed by MTT assay in MCF-7MIR210HG−OV and 231-7MIR210HG−OV cells with indicated treatments. I Colony formation assay of MCF-7MIR210HG−OV cells with indicated treatments. Quantification was presented. J Transwell assay of MCF-7MIR210HG−OV cells with indicated treatments. Quantification was presented. **p < 0.01, ***p < 0.001